How food affects long-term cognitive function


Dr Libby (PhD) shares how important nourishment is to your brain health now and into the future.

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  • Health
  • Read Time: 5 mins

Key Points


  • Research links your daily food choices to memory, concentration, and dementia risk.  

  • When oxidative stress and chronic low-grade inflammation persist over long periods without adequate protective mechanisms to regulate them, they may contribute to damage within brain cells and blood vessels. 

  • Higher ultra-processed food intake has been associated with poorer attention and increased dementia risk across multiple observational studies.   

  • Research consistently points towards eating patterns centred on whole, minimally processed foods being associated with better cognitive ageing outcomes. 

  • Small, sustainable choices repeated regularly are likely to have a far greater impact on long-term health than short bursts of restrictive eating or the latest wellness trend.

We don’t often think about how the food we eat today shapes our future health, but the reality is that what we eat quite literally becomes part of us. 

The foods we consume regularly help nourish every single cell in the body, supporting the ongoing processes of rebuilding, repair, and renewal that keep us functioning well over time.  

Growing research also suggests our daily food choices may influence memory, concentration, and dementia risk as we age. So, what helps support long-term brain health – and what might the brain benefit from less of over time? 

The brain and inflammation  

Chronic inflammation and oxidative stress are now believed to play a significant role in cognitive decline and neurodegenerative diseases such as Alzheimer’s. 

Oxidation itself is a normal and necessary process within the body, and inflammation is also part of the immune system’s natural defence response. However, when oxidative stress and chronic low-grade inflammation persist over long periods without adequate protective mechanisms to regulate them, they may contribute to damage within brain cells and blood vessels, potentially accelerating age-related changes in cognitive function.  

Foods that drive inflammation  

Emerging research is also raising concerns about diets high in ultra-processed foods (UPFs). A recent Australian study involving more than 2,000 middle-aged and older adults found higher intake of UPFs was associated with poorer attention and increased modifiable dementia risk, even among people otherwise following nourishing dietary patterns. 

A 2024 systematic review published in the Journal of Neurology also found higher UPF intake was associated with increased dementia risk across multiple observational studies. 

UPFs are processed foods that contain ingredients not typically used in home cooking such as preservatives, emulsifiers, artificial flavours, colours, and stabilisers. They are usually designed to be highly convenient, hyper-palatable, and have a long-shelf life.  

Importantly, not all packaged foods are ultra-processed. Foods such as rice, tomato passata, frozen vegetables, and grains like rolled oats are processed to some degree, but minimally, so much so that you can still recognise the foods they are. These can absolutely form part of a nutritious diet.  

So, if you are looking to make one meaningful dietary change, reducing your intake of ultra-processed foods and replacing them with more minimally processed options and whole foods, may have a significant impact on long-term health, including brain health.

Foods that calm inflammation  

Research consistently points towards eating patterns centred on whole, minimally processed foods being associated with better cognitive ageing outcomes. 

The Mediterranean diet – a way of eating rich in vegetables, fruit, legumes, nuts, olive oil and fish – has repeatedly been linked with slower cognitive decline and lower dementia risk. So what nutrients and plant compounds feature heavily in this style of eating?  

Omega 3s and other whole food fats 

Omega-3 fatty acids are among the most researched nutrients when it comes to brain health. In particular, DHA, a type of omega-3 fat found in oily fish, forms part of brain cell membranes and plays an important role in how brain cells communicate with one another. Omega-3s are also thought to help regulate inflammation in the body. 

Foods rich in omega-3s include salmon (make sure it is wild, not farmed), sardines, mackerel, and trout, as well as walnuts, chia seeds, and flaxseeds. Extra virgin olive oil, another staple of Mediterranean-style eating patterns, has also been associated with better cardiovascular and cognitive health outcomes. 

Antioxidants and polyphenols  

Antioxidants help neutralise unstable molecules known as free radicals, which can contribute to oxidative stress and cellular damage over time. 

Many colourful plant foods are naturally rich in antioxidants, including berries, leafy greens, tomatoes, and herbs and spices. 

Polyphenols are another group of naturally occurring plant compounds attracting increasing interest in brain health research. Found in foods such as berries, olive oil, tea, coffee, dark chocolate, and deeply coloured vegetables, polyphenols may help support healthy blood flow to the brain while helping reduce inflammation and oxidative stress. 

While no single food can guarantee protection against cognitive decline, consistently eating a wide variety of colourful plant foods appears to offer cumulative benefits over time. 

Dietary patterns over perfection  

Food messaging has become increasingly confusing in recent years. Yet when it comes to supporting long-term brain health, what you can see is that the evidence continues to point back to relatively simple foundations. 

Rather than focusing on perfection or chasing individual “superfoods”, research suggests it is overall dietary patterns that matter most. Eating a wide variety of whole, minimally processed foods most of the time – including vegetables, fruit, legumes, nuts, wholegrains (if you digest them well), nourishing fats, and quality sources of protein – provides the brain with the nutrients it needs to function, repair and adapt over time. 

When it comes to red meat, choose grass fed and finished, and leave the ultra-processed deli meats with all of their additives on the shelf. 

Importantly, this is not about eating perfectly. Small, sustainable choices repeated regularly are likely to have a far greater impact on long-term health than short bursts of restrictive eating or the latest wellness trend. 

And perhaps that brings us back to something refreshingly simple: eating more real food, more often. 

Author

Dr Libby

Dr Libby

Dr Libby has a Bachelor of Health Science (Nutrition and Dietetics) (Hons), a PhD in Biochemistry, and 25 years of clinical experience. Subscribe to Health Matters below.

Disclaimer: This article is for information purposes only and should not be considered medical advice. Consult a healthcare professional about any health concerns or before making any changes to your medication, diet, or exercise routine. 

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